Objective monitoring tools are urgently required to address the large healthcare burden of asthma, the most common chronic respiratory condition among children in the developed world, with 300 million sufferers worldwide and significant ongoing morbidity and mortality. Attempts to reduce ongoing exacerbation risks with early use of increased inhaled cortiscosteroids have been unsuccessful, resulting in a call to better understand the nature of asthma in adults but is of limited use in pediatric asthma owing to its effort-dependent nature. A more pratical and clinically informative signal of lung function variability is needed to capture the degree of variable airflow obstruction present, which, in addition to airway hyperresponsiveness, is a fundamental physiological characteristic of asthma.
Home-based Forced Oscillation Technique Day-to-Day Variability in Pediatric Asthma
May 6, 2020 / in Scientific articles / by Eve-Gabrielle Bissonnette
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