Accéder au contenu:

Résumé de recherche

Background

To determine normative data by forced oscillation technique (FOT) in non-sedated normal term neonates and test the hypothesis that infants with transient tachypnea of the newborn (TTN) have higher resistance (R) and lower reactance (X) on day 1.

Methods

Healthy term infants (n = 138) and infants with TTN (n = 17) were evaluated on postnatal days 1 through 3 (NCT03346343). FOT was measured with a mask using a TremoFlo C-100 Airwave System™. R, X, and area under the reactance curve (AX) were measured at prime frequencies 7–41 Hz for 8 s.

Results

In all, 86% of control infants had adequate measurements (coherence >0.8, CV < 0.25) on day 1. Infants with TTN had higher resistance at 13 Hz (TTN 32.5 cm H2O·s/L [95% CI 25.5–39.4]; controls 23.8 cm H2O·s/L [95% CI 22.2 to 25.3], P = 0.007) and lower reactance from 17 to 37 Hz (TTN −35.1 to −10.5; controls −26.3 to −6.1, P < 0.05). In healthy controls, lung mechanics were unchanged from days 1 to 3. In TTN, lung mechanics normalized on days 2 and 3.

Conclusions

FOT is feasible in neonates and distinguishes normal control infants from those with TTN on postnatal day 1. Oscillometry offers a non-invasive, longitudinal technique to assess lung mechanics in newborns.

Source

Klinger AP, Travers CP, Martin A, Kuo HC, Alishlash AS, Harris WT, et al. Non-invasive forced oscillometry to quantify respiratory mechanics in term neonates. Pediatr Res. 2020.

Nous contacter
Dites-nous comment nous pouvons vous aider. Nous serions heureux d'avoir de vos nouvelles !
Vous êtes intéressés par les produits THORASYS ? Contactez-nous pour obtenir un devis personnalisé.
Formulaire soumis avec succès !
Nous vous contacterons sous peu.